Merger between Hamlet Pharma AB and SelectImmune Pharma AB. VISIT SELECTIMMUNE WEBSITE

Merger between Hamlet Pharma AB and SelectImmune Pharma AB. VISIT SELECTIMMUNE WEBSITE


Hamlet Pharma secures long-term Alpha1 peptide production in an agreement with Polypeptide Group

By June 12, 2023 No Comments

Lund, June 12, Hamlet Pharma, ticker HAMLET, soon to be Hamlet BioPharma, the innovative pharmaceutical company with a strong portfolio of projects for the treatment of cancer and infections, announces that Hamlet Pharma has extended and expanded the agreement with the Swiss public company Polypeptide Group, ticker PPGN, to produce larger quantities of the synthetic peptide Alpha1. The new production, at a larger scale, will be essential for future expansions of the clinical trial program in bladder cancer. 

”We value the continued collaboration with Polypeptide group, which is essential to supply Alpha1H to the patients. Our partnership with Polypeptide Group and the large-scale manufacturing is one of the highest priorities for our expansion of the clinical trial program in bladder cancer” says Catharina Svanborg, CMO and chairman of the board of Hamlet Pharma AB.

The drug candidate Alpha1H is produced in two steps. The Alpha1 peptide is synthesized separately and then mixed with other constituents to form Alpha1H for clinical trials. Large scale synthesis methods have been developed together with Polypeptide Group in Strasbourg and Malmö, at GMP (Good Manufacturing Practice) quality, and the product has shown excellent stability.

The production of synthetic Alpha1H is now expanded to ensure larger quantities of the peptide and guarantee continued access to the peptide for clinical studies. This requires a technical development step to scale up the current production protocol, as well as the production of kilogram quantities of the peptide, at the Polypeptide production site in Malmö, Sweden. Polypeptide Group is a widely recognized international supplier of peptides for clinical trials and established drugs. 

For more information, please contact

Catharina Svanborg, Chairman and founder of Hamlet Pharma, +46-709 42 65 49

Martin Erixon, CEO Hamlet Pharma, +46 733 00 43 77

Visit our websites for more information

Read in PDF >>

Hamlet Pharma

Author Hamlet Pharma

More posts by Hamlet Pharma

Hamlet Pharma AB

Klinikgatan 32
SE-222 42 Lund, Sweden
+46 40 12 25 00